Oncogenes and Tumor Suppressor Genes in Photocarcinogenesis
نویسندگان
چکیده
منابع مشابه
Oncogenes and tumor suppressor genes.
The genetic paradigm of cancer — that tumors arise as a consequence of the accumulation of mutations in genes controlling cell proliferation, differentiation or death — is now widely accepted. The purpose of this is lecture provide a review of current knowledge on the various types of cancer genes identified so far in different stages of tumor development. We will also address recent attempts t...
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Genetic instability is a hallmark of cancer. Alterations in DNA through mutations, deletions, and translocations affect genes that are fundamental to normal cell growth differentiation and programmed cell death. Here, we discuss these alterations as they relate to oncogenes and tumor suppressor genes. In addition, we describe the implications the changes in oncogenes and tumor suppressor genes ...
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Invariably mesothelioma is diagnosed late in the development of the disease when treatment is no longer effective. Therefore, a key to reducing the mortality rate of this neoplasm is knowledge of the general sequence of genetic events between initiation of mesothelial cells and the emergence of the metastatic tumor cells. Unfortunately, relatively little is known about the early changes in the ...
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ژورنال
عنوان ژورنال: Photochemistry and Photobiology
سال: 1996
ISSN: 0031-8655,1751-1097
DOI: 10.1111/j.1751-1097.1996.tb03063.x